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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GRM2
All Species:
25.15
Human Site:
Y528
Identified Species:
46.11
UniProt:
Q14416
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14416
NP_000830.2
872
95568
Y528
L
C
I
P
C
Q
P
Y
E
Y
R
L
D
E
F
Chimpanzee
Pan troglodytes
A3QNZ8
839
95029
R498
P
V
S
M
C
S
K
R
C
Q
S
G
Q
K
K
Rhesus Macaque
Macaca mulatta
A3QP01
839
95041
R498
P
V
S
M
C
S
K
R
C
Q
S
G
Q
K
K
Dog
Lupus familis
XP_541867
872
95696
Y528
L
C
I
P
C
Q
P
Y
E
Y
R
L
D
E
F
Cat
Felis silvestris
Mouse
Mus musculus
Q14BI2
872
95869
Y528
L
C
I
P
C
Q
P
Y
E
Y
R
L
D
E
F
Rat
Rattus norvegicus
P31421
872
95755
Y528
L
C
I
P
C
Q
P
Y
E
Y
R
L
D
E
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518731
870
95758
Y528
L
C
I
P
C
Q
P
Y
E
Y
L
R
D
Q
F
Chicken
Gallus gallus
XP_416842
879
98936
Y537
I
C
I
P
C
E
T
Y
E
Y
L
A
D
E
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5U9X3
867
97118
S526
T
C
V
E
N
H
Y
S
N
I
T
D
A
D
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91685
976
108467
F587
I
C
D
S
C
E
S
F
E
Y
V
Y
D
E
F
Honey Bee
Apis mellifera
NP_001011624
933
103448
Y566
V
C
D
Q
C
E
E
Y
E
Y
V
Y
D
E
Y
Nematode Worm
Caenorhab. elegans
Q09630
999
113258
L642
K
C
E
D
Y
E
Y
L
I
N
E
T
H
C
V
Sea Urchin
Strong. purpuratus
XP_784936
1474
165598
W1111
M
C
I
K
C
Q
P
W
E
Y
L
Q
N
E
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
27.6
27.6
98.1
N.A.
97.4
97.8
N.A.
88.3
67.9
N.A.
25.5
N.A.
45.7
47
39.9
32.2
Protein Similarity:
100
46.3
46.3
98.9
N.A.
98.5
98.7
N.A.
92.7
82.2
N.A.
43.8
N.A.
61.7
63.3
55.6
43.4
P-Site Identity:
100
6.6
6.6
100
N.A.
100
100
N.A.
80
66.6
N.A.
6.6
N.A.
46.6
46.6
6.6
53.3
P-Site Similarity:
100
13.3
13.3
100
N.A.
100
100
N.A.
86.6
80
N.A.
20
N.A.
66.6
66.6
13.3
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
8
8
0
0
% A
% Cys:
0
85
0
0
85
0
0
0
16
0
0
0
0
8
0
% C
% Asp:
0
0
16
8
0
0
0
0
0
0
0
8
62
8
0
% D
% Glu:
0
0
8
8
0
31
8
0
70
0
8
0
0
62
8
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
54
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
16
0
0
0
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
0
8
0
0
% H
% Ile:
16
0
54
0
0
0
0
0
8
8
0
0
0
0
0
% I
% Lys:
8
0
0
8
0
0
16
0
0
0
0
0
0
16
16
% K
% Leu:
39
0
0
0
0
0
0
8
0
0
24
31
0
0
0
% L
% Met:
8
0
0
16
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
0
0
8
8
0
0
8
0
0
% N
% Pro:
16
0
0
47
0
0
47
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
8
0
47
0
0
0
16
0
8
16
8
0
% Q
% Arg:
0
0
0
0
0
0
0
16
0
0
31
8
0
0
0
% R
% Ser:
0
0
16
8
0
16
8
8
0
0
16
0
0
0
0
% S
% Thr:
8
0
0
0
0
0
8
0
0
0
8
8
0
0
0
% T
% Val:
8
16
8
0
0
0
0
0
0
0
16
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
16
54
0
70
0
16
0
0
16
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _